| Durham University student Irvin captained England to a historic victory over the French in Cahors two weeks ago, their first in 14 years, and will be hoping to repeat the feat when the sides meet again.
The game will be the last international for Tony Lanaway, who bows out after 12 years managing the side.
On the eve of the RBS 6 Nations clash with France at Twickenham it's also an opportunity for the students to stress their role in developing young players with three old boys in the senior side.
"We're delighted to have been able to select the same squad again that did so heroically in Cahors," said Lanaway.
"Steve Hill and Patrick Jerran have been able to work hard on attacking with the squad this week and we're hoping to expand that side of our game and give spectators a treat.
"All the squad are thrilled that three former England Students players are in senior side this weekend in the shape of Dave Strettle, Nick Easter and Tim Payne and the student game still has an important role to play in developing young players."
England Students:
15 Jack Smales (Bath)
14 Tom Jarvis (Hartpury College)
13 David Tibbott (Cambridge)
12 Thomas Gregory (Nottingham)
11 Ryan Owen (Loughborough)
10 Alastair Simmie (Durham)
9 Toby Henry (Loughborough)
1 Kevin Davis (Loughborough)
2 Joe Clark (Cambridge)
3 Aaron Liffchak (Hertfordshire)
4 Ian Kench (Loughborough)
5 Jon Chance (Oxford)
6 Douglas Abbott (Oxford)
7 Tom Malaney (Cambridge)
8 Greg Irvin (Durham)
Replacements:
16 Richard Lutton (Loughborough)
17 Daniel James (Loughborough)
18 Robert Anderson (Imperial)
19 Tom George (Nottingham)
20 Toby Henry (Loughborough)
21 Rory Damant (St Mary's)
22 Duncan Steele (Bath)
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