| Flood returns to the side at fly half following a knee injury, while Wilson continues at tight head prop, where he has started every game for England during the competition.
“Toby has been a part of our plans from the start,” said coach Jim Mallinder.
“Unfortunately he got injured, but we’ve been lucky to have good strength in the midfield and great options to choose from. Toby will bring the experience he’s gained playing in this year's Guinness Premiership to such an important game.”
The fixture, billed as a championship decider, will determine which team goes into the final round unbeaten.
“The French are a very strong side with a good record in this championship, and they certainly won’t want their first loss to be against us especially in front of a home crowd,” said Mallinder.
“We expect a very tough game but we’re well prepared and looking forward to the challenge.”
England Under-21s:
15. Mike Brown – NEC Harlequins
14. Thom Evans – London Wasps
13. Matt Cornwell – Leicester Tigers (captain)
12. Anthony Allen – Gloucester
11. Nick Abendanon – Bath Rugby
10. Toby Flood – Newcastle Falcons
9. Ben Foden – Sale Sharks
1. Alex Rogers – NEC Harlequins
2. Dylan Hartley – Northampton Saints
3. David Wilson – Newcastle Falcons
4. Richard Blaze – Worcester Warriors
5. Tom Croft – Leicester Tigers
6. James Haskell – London Wasps
7. Michael Hills – Sale Sharks
8. Jordan Crane – Leeds Tykes
Replacements:
16. Neil Briggs – Sale Sharks
17. Mark Lambert – NEC Harlequins
18. Sean Cox – Sale Sharks
19. Alex Rae – Northampton Saints
20. Nick Runciman – Worcester Warriors
21. Ryan Lamb – Gloucester
22. Topsy Ojo – London Irish
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